End-stage renal disease, also called end-stage kidney disease or kidney failure, occurs when chronic kidney disease — the gradual loss of kidney function — reaches an advanced state. In end-stage renal disease, your kidneys no longer work as they should to meet your body's needs. 

When you have chronic kidney disease(CKD), your kidneys slowly stop working properly. The damage is lasting and can get worse over time, leading to different stages of chronic kidney disease. 


Kidney failure can be divided in to several stages according to its severity - Stage 1 to 5. 

End Stage Renal Failure is said to occur when the kidney function is at stage 5. You would require renal replacement Therapy to stay alive at the stage. 

The Malaysian National Health and Morbidity Survey 2011 showed a prevalence of 9.07% in adults with CKD, and only 4% of respondents were aware of the diagnosis. There were 37,183 patients on regular dialysis in 2015, with 7,595 new patients entering dialysis. The number of Malaysians with CKD is projected to significantly increase in the future mainly due to the increasing prevalence of diabetes, hypertension and the aging population. 

CKD is a common but silent and often under-recognized condition. 

There is no cure for chronic kidney disease, but early diagnosis and treatment can help stop your disease from worsening.  

Many people live long and normal lives with CKD, but it’s important to see your doctor regularly to manage your condition. 

Recommendation screening for early detection:

If you have diabetes mellitus and/or hypertension should do the screening at least yearly for chronic kidney disease (CKD).  And also If you have other high risk factors such as below:

  •  Age >65 years old  
  • Obesity 
  • Cardiovascular disease  
  • Metabolic syndrome  
  • Family history of CKD or hereditary kidney disease  
  • Gout  
  • Multisystem diseases with potential kidney involvement e.g. systemic lupus erythematosus 

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